GIDRM DAY – Exploring diagnostic probes and procedures beyond Gd(III) for MRI applications
Informations
Recently, the use of Gd3+ chelates as contrast agents (CAs) in MRI has encountered two significant challenges. The first arose, ca. 20 years ago, with the occurrence of nephrogenic systemic fibrosis (NSF) in patients with renal impairment who had undergone contrast-enhanced MRIs, prompting safety concerns regarding Gd3+ chelates. While regulations restricting CA use in renally compromised patients have mitigated NSF cases, apprehensions regarding safety persist. Additionally, the environmental impact of CAs in MRI is becoming evident. Gd3+, typically sequestered in the lithosphere, is now detectable at elevated levels in drinking water sources and marine ecosystems. Addressing these challenges is imperative. This workshop aims to explore potential alternatives and discuss future directions.
Scientific Committee
Mauro Botta, University of Piemonte Orientale
Michele Chierotti, University of Torino
Silvia Borsacchi, CNR-ICCOM, Pisa
Simonetta Geninatti Crich, University of Torino
Giacomo Parigi, University of Firenze
Antonio Randazzo, University of Napoli Federico II
Laura Ragona, SCITEC-CNR, Milano
Luigi Russo, University of Campania
Organising Committee
Mauro Botta (DiSIT, University of Piemonte Orientale)
Fabio Carniato (DiSIT, University of Piemonte Orientale)
Daniela Lalli (DiSIT, University of Piemonte Orientale)
Alessandro Nucera (DiSIT, University of Piemonte Orientale)
Marco Ricci (DiSIT, University of Piemonte Orientale)
Maria Ludovica Macchia (DiSIT, University of Piemonte Orientale)
Claudio Cassino (DiSIT, University of Piemonte Orientale)
Lorenzo Risolo (DiSIT, University of Piemonte Orientale)
Giovanni B. Giovenzana (DSF, University of Piemonte Orientale)
Federico Forgione (DSF, University of Piemonte Orientale)
Fabio Travagin (DSF, University of Piemonte Orientale)
Sponsors
With the endorsement of:
This conference is part of the project NODES which has received funding from the MUR – M4C2 1.5 of PNRR funded by the European Union – NextGenerationEU (grant agreement no. ECS00000036).
Registration & Fees
Deadline
The registration deadline is May 10th, 2024
Fee
60€ for non-GIDRM members (the fee includes GIDRM 2024 subscription);
40€ for GIDRM members.
The registration fee includes the access to the Scientific Sessions, coffee Break and Lunch.
A limited number of PhD students from the University of Eastern Piedmont Amedeo Avogadro are eligible for free registration. Please write to alessandria2024@gidrm.org to ask for a coupon.
To attend the event, you must purchase the ticket of your choice at the top of this page.
You must be registered and logged into the GIDRM website to purchase tickets.
To complete the purchase, you will need to complete the registration form.
– If you don’t have an account yet, create one on the home page of the site by clicking below on the red “Become a member” button (the account on the old site is no longer valid) and selecting “Free Membership”. After a succesful registration log in into your new account, return to this page and buy the ticket you want;
– If you are already registered or a GIDRM member, please login to your account and go to the top of this page and buy the ticket.
The registration fee can be paid by Credit Card or PayPal or Bank Transfer. In order to pay by bank transfer please contact pagamenti@gidrm.org.
In the case you should encounter any difficulty in filling the form, please contact us by e-mail at: alessandria2024@gidrm.org
The Venue
The Event will be held at the Dipartimento di Scienze ed Innovazione Tecnologica, University of Piemonte Orientale, Viale Teresa Michel 11, Alessandria, Room 101.
How to reach us
By train:
Alessandria station – 20 min walk or 5 min by bus Line AC or Line 4. During peak hours, buses run at approximately 20-minute intervals. Ticket available on the bus, in the station (Tobacconist shop) and online https://www.amagmobilita.it/trasporti-alessandria/orari-autobus-alessandria.
By car:
From Milan. Highway A7, take the A21 direction, exit Alessandria Ovest.
From Turin. Highway A21, exit Alessandria Ovest.
Invited Speakers
Dario Longo (IBB/CNR)
Daniela Delli Castelli (UniTO)
Alessandro Lascialfari (UniPV)
Francesca Baldelli Bombelli (PoliMI)
Giacomo Parigi (UniFI)
Lorenzo Tei (UPO)
Alessandro Nucera (UPO)
Fabio Carniato (UPO)
Zsolt Baranyai (Bracco Research Center)
Francesca Reineri (UniTO)
Mauro Botta (UPO)
Program
The event will be held in English.
9.15-9.45 Registration and welcome coffee
9.45-10.00 Welcome and opening
10.00-10.30 Dario Longo (UniTO) – Diamagnetic CEST-MRI contrast agents: an overview of molecules and of emerging applications
10.30-11.00 Daniela Delli Castelli (UniTO) – Addressing a significant hurdle: the low sensitivity of CEST contrast agents
11.00-11.30 Alessandro Lascialfari (UniPV) – Magnetic nanoparticles for MRI
11.30-12.00 Francesca Baldelli Bombelli (PoliMI) – 19F-MRI: from probe design to biomedical application
12.00-12.30 Giacomo Parigi (UniFI) – Manganese-rich fruit juices as oral MRI contrast agents
12.30-13.00 Lorenzo Tei (UPO) – Transition metal-based probes: Mn(II)
13.00-14.00 Lunch break
14.00-14.30 Alessandro Nucera (UPO) – Transition metal-based probes: Fe(III)
14.30-15.00 Fabio Carniato (UPO) – Transition metal-based probes: Cu(II) / V(IV)
15.00-15.30 Zsolt Baranyai (Bracco Research Center) – Exploring thermodynamic and kinetic attributes for the design of metal chelates as alternatives to Gd(III)-based probes
15.30-16.00 Francesca Reineri (UniTO) – Hyperpolarized molecules for biomedical imaging
16.00-16.20 Mauro Botta (UPO) – In the interim: reducing doses by optimizing the efficacy of Gd(III) probes
Accommodation
Accommodation is NOT included in the registration fee.
Participants are kindly invited to book their own hotel rooms. Here a few suggestions:
a) Hotel Europa (***), Via Palestro 1 – https://www.hoteleuropaal.it
b) Hotel Domus (***),Via T. Castellani, 12 – https://domus-hotel-alessandria.hotelmix.it/
c) Hotel Londra (****), Corso F. Cavallotti 51 – www.londrahotel.info